NFL Picks

Upcoming games, lines and context for the week.

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16 games · 2026 regular season, week 4

Indianapolis Colts Favored
1-2
at
Washington Commanders
1-2
Sun Oct 4, 9:30 AM ET
NFL Net
Tottenham Hotspur Stadium
ESPN Matchup Predictor IND 56% to win Public bets vs pick WSH 58% of bets Money IND 62% of handle
New England Patriots
1-2
at
Buffalo Bills Favored
3-0
Sun Oct 4, 1:00 PM ET
CBS
Highmark Stadium
DraftKings BUF -7 ESPN Matchup Predictor BUF 70% to win Public bets BUF 66% of bets Money BUF 67% of handle
New York Jets
1-2
at
Chicago Bears Favored
2-1
Sun Oct 4, 1:00 PM ET
FOX
Soldier Field
DraftKings CHI -3.5 ESPN Matchup Predictor CHI 68% to win Public bets CHI 53% of bets Money vs pick NYJ 51% of handle
Jacksonville Jaguars
2-1
at
Cincinnati Bengals
2-1
Sun Oct 4, 1:00 PM ET
CBS
Paycor Stadium
Sources split DraftKings CIN -2.5 ESPN Matchup Predictor JAX 54% to win Public bets JAX 64% of bets Money JAX 61% of handle
Arizona Cardinals Favored
1-2
at
New York Giants
2-1
Sun Oct 4, 1:00 PM ET
CBS
MetLife Stadium
DraftKings ARI -2.5 ESPN Matchup Predictor ARI 52% to win Public bets ARI 59% of bets Money vs pick NYG 51% of handle
Los Angeles Rams Favored
1-2
at
Philadelphia Eagles
2-1
Sun Oct 4, 1:00 PM ET
FOX
Lincoln Financial Field
DraftKings LAR -3.5 ESPN Matchup Predictor LAR 64% to win Public bets LAR 53% of bets Money vs pick PHI 61% of handle
Green Bay Packers Favored
1-2
at
Tampa Bay Buccaneers
0-3
Sun Oct 4, 1:00 PM ET
FOX
Raymond James Stadium
DraftKings GB -3 ESPN Matchup Predictor GB 68% to win Public bets GB 54% of bets Money vs pick TB 51% of handle
Tennessee Titans
0-3
at
Baltimore Ravens Favored
2-1
Sun Oct 4, 1:00 PM ET
CBS
M&T Bank Stadium
DraftKings BAL -11.5 ESPN Matchup Predictor BAL 84% to win Public bets BAL 73% of bets Money BAL 81% of handle
Dallas Cowboys
1-2
at
Houston Texans
0-3
Sun Oct 4, 1:00 PM ET
FOX
Reliant Stadium
Sources split DraftKings HOU -3 ESPN Matchup Predictor DAL 55% to win Public bets DAL 83% of bets Money DAL 83% of handle
Miami Dolphins
0-3
at
Minnesota Vikings Favored
3-0
Sun Oct 4, 4:05 PM ET
FOX
U.S. Bank Stadium
DraftKings MIN -10 ESPN Matchup Predictor MIN 83% to win Public bets MIN 74% of bets Money MIN 61% of handle
Kansas City Chiefs Favored
3-0
at
Las Vegas Raiders
3-0
Sun Oct 4, 4:25 PM ET
CBS
Allegiant Stadium
DraftKings KC -4.5 ESPN Matchup Predictor KC 70% to win Public bets KC 52% of bets Money KC 58% of handle
Denver Broncos
2-1
at
San Francisco 49ers Favored
3-0
Sun Oct 4, 4:25 PM ET
CBS
Levi's Stadium
DraftKings SF -3 ESPN Matchup Predictor SF 78% to win Public bets SF 60% of bets Money SF 64% of handle
Los Angeles Chargers
0-3
at
Seattle Seahawks Favored
2-1
Sun Oct 4, 4:25 PM ET
CBS
Lumen Field
DraftKings SEA -7 ESPN Matchup Predictor SEA 74% to win Public bets SEA 56% of bets Money SEA 52% of handle
Detroit Lions Favored
2-1
at
Carolina Panthers
1-2
Sun Oct 4, 8:20 PM ET
NBC
Bank of America Stadium
DraftKings DET -3.5 ESPN Matchup Predictor DET 61% to win Public bets DET 63% of bets Money DET 67% of handle
Pittsburgh Steelers Favored
2-2
at
Cleveland Browns
3-1
Thu Oct 1, 8:15 PM ET
Prime Video
Huntington Bank Field
Betting against the pick ESPN Matchup Predictor PIT 55% to win Public bets vs pick CLE 59% of bets Money vs pick CLE 53% of handle
Atlanta Falcons
1-2
at
New Orleans Saints Favored
1-2
Mon Oct 5, 8:15 PM ET
ESPN
Caesars Superdome
Betting against the pick DraftKings NO -1.5 ESPN Matchup Predictor NO 63% to win Public bets vs pick ATL 54% of bets Money vs pick ATL 70% of handle